Detection of stem cells in human endometrium: immune-histochemical study

In this work, we recruited CD105 and CD90 markers to identify the endometrial stem cells (EnSCs) in human uterine endometrium. Fifty specimens have been extracted from twenty-five deceased women. All embedded paraffin block prepared for immune-histochemical processing. The expression of was counted per high power field (HPF). Paired sample t-test used compare means between groups age variables. Statistical analysis conducted using “SPSS16 software" statistical significance considered at less than 0.05. Results paired showed that count (EC) Basalis layer (with CD105) 5.26 points higher Functionalis (95% CI [3.43, 7.09]) correlation strongly positively related (r = 0.829, P < 0.001). EC CD90) 4.96 [3.02, 6.89]) 0.746, P= 0.9 Stroma [2.27, 4.11]); however, weak 0.429, 0.032). 1.4 [2.1, 4.2]), but moderately r 0.547, 0.005). Findings an independent-sample Functionalis, Basalis, layers markers) more among patients reproductive (<50 years) who were non-reproductive (50 years above), a statistically significant difference [(m 9.6, 95% (5.3, 14.6), t (19.630) 4.413, 0.001)], 10.2, (5.2, 15.2), (20.714) 4.202, 0.001)] 8.4, (3.5, 13.4), (12.313) 3.523, 0.002)], respectively. conclusion, endometrium decreases with age.